EFFECTS OF STEROIDS ON TETRAHYMENA

1 January 1978

journal article
research article

Vol. 37 (9) , 1377-1380

Abstract

Phagocytosis of Tetrahymena pyriformis is inhibited by prednisolone-sodium-succinate and deoxycorticosterone-glucoside, and stimulated by dexamethasone and prednisolone. Dexamethasone and estradiol enter the cells and are localized 1st in food vacuoles, and later in the cytosol. They were never found in the nucleus. The demonstration by biochemical methods of a specific glucocorticoid binding protein failed in all 3 subcellular fractions examined.

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