Immunologic Aspects of Pinta

Publisher Website
Google Scholar
Abstract
Natural immunity was not observed in pinta. The immuno-allergic phenomena in pinta are less intensive than in syphillis and f rambesia: nevertheless the same kind of antibodies are developed by the 3 infections. Tuberculoid structure and Herxheimer reactions are not observed in pinta. There are 3 evolutive stages in pinta: primary, secondary and tertiary. Lesions of one stage may develop into lesions of the next stage, although latent periods may be observed. The evolution of pinta may be explained by immuno-allergic oscillations. Treponemata could be demonstrated in the lesions through all evolutive stages; their number is somehow reduced in tertiary lesions. Experimental inoculations demonstrated pan-immunity in late pinta. Homologous super-infection was possible in pre-serologic phase. Homologous super-infection in post-serologic phases produced lesions similar to the pre-existent ones (Finger-Landesteiner''s law). Reinfection could be obtained: the disease developed slowly in post-serologic cured cases. There is partial cross-immunity between syphillis, framboesia and pinta: most experimental inoculations of pinta are unsuccessful in syphilis and frambesis patients.

This publication has 0 references indexed in Scilit: