Calcineurin Is a Key Signaling Enzyme in T Lymphocyte Activation and the Target of the Immunosuppressive Drugs Cyclosporin A and FK506a
- 1 November 1993
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 696 (1) , 20-30
- https://doi.org/10.1111/j.1749-6632.1993.tb17138.x
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Identification of calcineurin as a key signalling enzyme in T-lymphocyte activationNature, 1992
- Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexesCell, 1991
- Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: One in the presence and one in the absence of CsACell, 1991
- FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytesCellular Immunology, 1991
- CyclosporineNew England Journal of Medicine, 1989
- The mechanism of action of the immunosuppressive drug FK-506Cellular Immunology, 1989
- A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilinNature, 1989
- FK-506 — How much potential?Immunology Today, 1989
- CalcineurinPublished by Wiley ,1988
- Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.The Journal of Experimental Medicine, 1986