CORRELATION OF ALVEOLAR P CO 2 ESTIMATED BY INFRA-RED ANALYSIS AND ARTERIAL P CO 2 IN THE HUMAN NEONATE AND THE RABBIT

Abstract
The performance of an infra-red analyser (Beckman LB-2) in sampling alveolar gas at ventilatory frequencies and volumes occuring in the human neonate has been examined. The optimum sampling flow rate was found to be 300 ml/min; at this flow the 90% response time of the analyser-catheter system was 140 ms. Correlation of estimated alveolar P2 and arterial PCO2 was performed in the rabbit which has a ventilatory rate and tidal volume similar to those of the human neonate. There was a good correlation between maximum end-expired PCO2 (PÉCO2) and arterial PCO2 over a wide range of ventilatory rates (10–100 b.p.m.); maximum PÉCO2 was a better index than mean PÉCO2 or alveolar plateau PÉCO2

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