4‐Azapteridines. I. Covalent addition products of the pyrazino[2,3‐e]‐as‐triazine ring system
- 1 July 1983
- journal article
- other
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 20 (4) , 1123-1125
- https://doi.org/10.1002/jhet.5570200458
Abstract
Ring closure of 5, 6‐diamino‐3‐methylthio‐as‐triazine with 40% aqueous glyoxal provided the 6, 7‐dihydrate of the pyrazino[2, 3‐e]‐as‐triazine (4‐azapteridine) ring system. The C7 hydroxy group of this dihydrate underwent exchange in methanol or ethanol affording the 7‐alkoxy, 6‐hydroxy derivatives.Keywords
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