Effects of Interferon-Alpha on Human Warts
- 1 January 1982
- journal article
- Published by Mary Ann Liebert Inc in Journal of Interferon Research
- Vol. 2 (2) , 235-243
- https://doi.org/10.1089/jir.1982.2.235
Abstract
Two patients with extensive warts which were stable for two years or more were treated with human interferon-alpha to assess the ability of interferon to affect this benign tumor of viral etiology. Intramuscular administration of 96.6 and 135 million units over 12-15 weeks produced softening and decreased scaling of each patient's warts. Double blind, placebo-controlled intralesional injections resulted in progressive disappearance of interferon treated warts. A dose response relationship was shown in eight warts. The minimum effective dose was 1.2 x 10(6) units injected over 15.5 weeks.Keywords
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