A Randomized Controlled Trial to Evaluate Antiretroviral Salvage Therapy Guided by Rules-Based or Phenotype-Driven HIV-1 Genotypic Drug-Resistance Interpretation With or Without Concentration-Controlled Intervention: The Resistance and Dosage Adapted Regimens (RADAR) Study
Open Access
- 15 June 2005
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 40 (12) , 1828-1836
- https://doi.org/10.1086/429917
Abstract
Background. It is not well defined whether concentration-controlled intervention (CCI) and rules-based human immunodeficiency virus (HIV) type 1 genotKeywords
This publication has 19 references indexed in Scilit:
- GENOPHAR: a randomized study of plasma drug measurements in association with genotypic resistance testing and expert advice to optimize therapy in patients failing antiretroviral therapy*HIV Medicine, 2004
- Treatment for Adult HIV InfectionJAMA, 2004
- Impact of different HIV resistance interpretation by distinct systems on clinical utility of resistance testingCurrent Opinion in Infectious Diseases, 2003
- Comparison between Rules‐Based Human Immunodeficiency Virus Type 1 Genotype Interpretations and Real or Virtual Phenotype: Concordance Analysis and Correlation with Clinical Outcome in Heavily Treated PatientsThe Journal of Infectious Diseases, 2003
- Therapeutic drug monitoring of nelfinavir and indinavir in treatment-naive HIV-1-infected individualsAIDS, 2003
- High Variability of Plasma Drug Concentrations in Dual Protease Inhibitor RegimensAntimicrobial Agents and Chemotherapy, 2003
- Methods for Integration of Pharmacokinetic and Phenotypic Information in the Treatment of Infection with Human Immunodeficiency VirusClinical Infectious Diseases, 2003
- PharmAdaptAIDS, 2002
- High Indinavir Cmin Is Associated With Higher Toxicity in Patients on Indinavir-Ritonavir 800/100 mg Twice-Daily RegimenJAIDS Journal of Acquired Immune Deficiency Syndromes, 2002
- Amprenavir Inhibitory Quotient and Virological Response in Human Immunodeficiency Virus-Infected Patients on an Amprenavir-Containing Salvage Regimen without or with RitonavirAntimicrobial Agents and Chemotherapy, 2002