Cultivation of Yeast in Earle's "L" Strain Mouse Cells in vitro.

1 July 1953

journal article
research article
Published by Frontiers Media SA in Experimental Biology and Medicine

Vol. 83 (3) , 584-585
https://doi.org/10.3181/00379727-83-20425

Abstract

Earle''s "L" strain mouse cells grown on glass, were inoculated with the yeast cell phase of Histoplasma capsulatum. In stained prepns. it is shown that numerous yeast cells develop intracellularly. The infected animal cells can be subcultured. This system should prove satisfactory in the cultivation of other pathogens, including fungi and also provide a method of studying the effects of therapeutic agents.

Keywords

HISTOPLASMA

This publication has 2 references indexed in Scilit:

THE UTILIZATION OF A PURE STRAIN OF MAMMALIAN CELLS (EARLE) FOR THE CULTIVATION OF VIRUSES INVITRO .1. MULTIPLICATION OF PSEUDORABIES AND HERPES SIMPLEX VIRUSES
1953
Histoplasma capsulatum in Tissue Culture.
Experimental Biology and Medicine, 1951