Myxoma of the nerve sheath Report of three cases, observations by light and electron microscopy and histochemical analysis
- 1 October 1985
- journal article
- research article
- Published by Wolters Kluwer Health in The American Journal of Dermatopathology
- Vol. 7 (5) , 423-430
- https://doi.org/10.1097/00000372-198510000-00004
Abstract
Findings by light and electron microscopy and histochemistry in three cases of myxoma of a nerve sheath are presented. The histochemical findings are compared with those obtained in identical studies done on two benign schwannomas, two neurofibromas, and a soft tissue myxoma. In addition, myxomatous changes in a peripheral nerve obtained at vagotomy were similarly studied. Morphologically, myxoma of the nerve sheath is a distinct neoplastic entity showing moderate cellular atypia and a characteristic tissue distribution. Histochemically, the neoplasm shows a mucopolysaccharide profile that categorizes it as a neoplasm of mesenchymal origin rich in highly sulfated acid mucins. Of particular note is its close histochemical similarity to a neurofibroma.Keywords
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