Abstract
The effect of large butter-fat meals on the blood of rabbits and dogs has been studied. Marked distortion of the red blood cells with adhesiveness and aggregation was observed. This was accompanied by slowing of the circulation and by changes in the surface tension of the plasma. In addition changes in the platelet counts, white blood counts, hematocrit and erythrocyte sedimentation rates were observed. Changes were also noted in the buffy coat, in the clotting time and in the nature of the clot.