KINETIC STUDIES ON CALCIUM-DEPENDENT POTASSIUM-TRANSPORT IN HUMAN RED BLOOD-CELLS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 12  (3) , 207-216
Abstract
The kinetics of the Ca-dependent K transport across the human red cell membrane were studied under experimental conditions allowing the separation of this step from the previous membrane events. Net K and tracer K fluxes were measured and a self-consistent model was constructed for calculating the ionic permeability values. All experimental results were interpreted by means of a non-saturable neutral K selective channel. In net K efflux measurements, the accompanying Cl movement was rate-limiting, and the charge-carrying Cl permeability of the red cell membrane was calculated.

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