A decade of caspases
Top Cited Papers
- 24 November 2003
- journal article
- review article
- Published by Springer Nature in Oncogene
- Vol. 22 (53) , 8543-8567
- https://doi.org/10.1038/sj.onc.1207107
Abstract
Caspases are a family of cysteine proteases that play important roles in regulating apoptosis. A decade of research has generated a wealth of information on the signal transduction pathways mediated by caspases, the distinct functions of individual caspases and the mechanisms by which caspases mediate apoptosis and a variety of physiological and pathological processes.Keywords
This publication has 305 references indexed in Scilit:
- A Novel Single Amino Acid Deletion Caspase-8 Mutant in Cancer Cells That Lost Proapoptotic ActivityJournal of Biological Chemistry, 2002
- Human caspase 12 has acquired deleterious mutationsBiochemical and Biophysical Research Communications, 2002
- Cell death induced by a caspase-cleaved transmembrane fragment of the Alzheimer amyloid precursor proteinCell Death & Differentiation, 2002
- Evidence That Caspase-13 Is Not a Human but a Bovine GeneBiochemical and Biophysical Research Communications, 2001
- Caspase-14: Analysis of Gene Structure and mRNA Expression during Keratinocyte DifferentiationBiochemical and Biophysical Research Communications, 2000
- Cathepsin B-Mediated Activation of the Proinflammatory Caspase-11Biochemical and Biophysical Research Communications, 1998
- Apoptosis-Associated Proteolysis of Vimentin in Human Prostate Epithelial Tumor CellsBiochemical and Biophysical Research Communications, 1998
- Nitric Oxide Reversibly Inhibits Seven Members of the Caspase Family via S-NitrosylationBiochemical and Biophysical Research Communications, 1997
- Apoptosis in the Pathogenesis and Treatment of DiseaseScience, 1995
- A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytesNature, 1992