CODE Chemotherapy with or without Recombinant Human Granulocyte Colony-Stimulating Factor in Extensive-Stage Small Cell Lung Cancer
- 1 January 1992
- journal article
- clinical trial
- Published by S. Karger AG in Oncology
- Vol. 49 (1) , 19-24
- https://doi.org/10.1159/000227106
Abstract
CODE therapy demonstrated high antitumor activity in extensive-stage small cell lung cancer (SCLC). Toxicity was acceptable in a regimen with a nine-cycle schedule. The results obtained in this study suggest that CODE therapy improves the outcome of patients with extensive-stage SCLC. The use of recombinant human granulocyte colony-stimulating factor may well reduce the duration and degree of neutropenia during CODE chemotherapy and increase the dose intensity, leading to further improvement of outcome.Keywords
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