Epileptic Manifestations and Vitamin B1Deficiency

Publisher Website
Google Scholar
Abstract
Sixteen of 50 consecutive neurological patients with a diagnosis of thiamine deficiency showed epileptic (10) or epileptiform (6) manifestations. A survey of the literature revealed only few reports on a possible relationship between epilepsy and thiamine deficiency. It appears that thiamine deficiency may provoke epileptic phenomena in those patients who have subclinical predisposition for seizures. The presence of irritative activity on electroence-phalographic recordings in the patients may be a consequence of a vitamin Bi deficiency state. The possible pathophysiological mechanisms by which thiamine deficiency may contribute to seizure activity of the brain are discussed.

This publication has 0 references indexed in Scilit: