LYMPHOMA OF THE EYE AND ADNEXA

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Abstract
Lymphoma, otherwise malignant lymphoma or lymphoblastoma, is a generic term applied to malignant neoplastic diseases of the lymphoid and hematopoietic tissues. Ocular changes have been observed in cases of the following types of lymphoma: (1) sclerosing (Hodgkin's disease) ; (2) endothelial (lympho-endothelioma) ; (3) lymphoblastic (lymphosarcoma), and (4) lymphocytic (lymphatic leukemia). These invariably fatal diseases are closely related and are characterized by hyperplasia and metaplasia of the lymphoid and blood-forming tissues, with enlargement of the lymph nodes, spleen and liver and changes in the bone marrow. Characteristically, all types of lymphoma show progressive, painless enlargement of the cervical and other lymph nodes, increase in size of the spleen and liver and, in the later stages, secondary anemia and cachexia. There may be remittent fever, and pressure from enlarged glands may give rise to secondary symptoms, such as edema, pleural effusions, anasarca, dyspnea, dysphagia and so forth. Only in lymphatic leukemia is

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