FOLLICLE-STIMULATING HORMONE (FSH) AND INTERSTITIAL-CELL-STIMULATING HORMONE (ICSH) IN PITUITARY AND PLASMA OF INTACT AND OVARIECTOMIZED PROTEINDEFICIENT RATS12

Publisher Website
Google Scholar
Abstract
Absence of dietary protein in female rats caused a moderate increase in hypophyseal FSH content, whether expresssed per anterior pituitary or per milligram of tissue. The ICSH content in the hypophysis was unchanged from control levels per pituitary gland, though increased per milligram of tissue. Ovariectomy of protein-deficient rats further elevated pituitary content of both gonadotrophins, FSH and ICSH, raised the circulating levels of FSH and was accompanied by typical castration changes in the hypophysis. These morphological and physiological changes show that the pituitary gland, even in the complete absence of dietary protein, retained its capacity to respond to stimulus with increased synthesis and release of gonadotrophins.

This publication has 0 references indexed in Scilit: