Dendritic cell counts in the peripheral blood of healthy adults
- 28 March 2005
- journal article
- Published by Wiley in American Journal of Hematology
- Vol. 78 (4) , 314-315
- https://doi.org/10.1002/ajh.20296
Abstract
The normal range for adult blood dendritic cells (DC) has not been established. Blood DC counts were assayed directly from blood for 16 female and 11 male healthy adults with an age range of 22-60 years old (median, 46 years). DC were defined as lineage 1-negative/dim, CD34-negative/dim, and HLA-DR-positive within the total peripheral blood leukocyte (PBL) population. Impedance counter complete blood counts were used with flow cytometry percentages to calculate the absolute DC count and DC percentage of mononuclear cells (MNC). The normal adult ranges for DC calculated as the mean +/- 2SD were 0.16-0.68% PBL, 0.55-1.63% MNC, and 13-37 DC/microL of blood.Keywords
This publication has 5 references indexed in Scilit:
- Low dendritic cell count after allogeneic hematopoietic stem cell transplantation predicts relapse, death, and acute graft-versus-host diseaseBlood, 2004
- Monitoring dendritic cells in clinical practice using a new whole blood single-platform TruCOUNT assayJournal of Immunological Methods, 2003
- Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infectionBlood, 2001
- Monitoring Human Blood Dendritic Cell Numbers in Normal Individuals and in Stem Cell TransplantationBlood, 1999
- The effect of AZT on dendritic cell number and provirus load in the peripheral blood of AIDS patients: a preliminary studyResearch in Virology, 1996