Calcium Spike Electrogenesis and Other Electrical Activity in Continuously Cultured Small Cell Carcinoma of the Lung
- 5 June 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 212 (4499) , 1155-1157
- https://doi.org/10.1126/science.6262914
Abstract
Spike electrogenesis, local depolarizing and hyperpolarizing responses, spontaneous rhythmic firing, and alternating resting potentials were measured in cells from a continuously cultured small cell carcinoma of the lung. Spike generation was blocked by MnCl2. In view of this evidence for calcium-spike electrogenesis and previous evidence of secretory activity in these cells, this cell line (DMS 53) can provide a model for the study of excitation-secretion behavior in human neoplastic cells.This publication has 12 references indexed in Scilit:
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