PRECAUTIONS IN THE USE OF METHYLENE-BIS-o-CHLOROANILINE (MBOCA)

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Abstract
Methylene-bis-o-chloroaniline (MBOCA) is used in the production of moulded articles with a hard integral skin from polyurethane foam and also hard urethane rubbers. Animal experiments using rats had previously shown a high incidence of cancers. Subsequent experiments using dogs have so far been negative and there have been no cases of human cancer attributable to MBOCA. Nevertheless it is a substance which should be used under strict control and supervision. All processes involving MBOCA—handling, weighing, melting and mixing—should be carried out under exhaust ventilation. Inhalation of the dust or vapour and contamination of the skin or clothing should be avoided. Good housekeeping and personal cleanliness are also very important in preventing absorption of MBOCA.

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