ALKALINE PHOSPHATASE ACTIVITY AND SYNTHESIS OF INTESTINAL PHOSPHOLIPIDS

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Abstract
Alkaline phosphatase was investigated in small intestine of mice fed with different diets. A distinct increase of the enzyme activity after fat feeding has been shown both by cytochemical and biochemical methods. A pronounced response of Golgi localized alkaline phosphatase to fat feeding and a correlation of the amounts of this enzyme activity with the presence of intraepithelial lipid was observed. At the same time, brush border phosphatase seemed to be unrelated to presence of or feeding of fat. The relation of these findings to the previously reported or demonstrated intracellular phospholipid synthesis is discussed.

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