A Common Surface Antigen in Influenza Viruses from Human and Avian Sources

Open Access
Publisher Website
Google Scholar
Abstract
Serological cross-reactions were detected between four avian influenza viruses and a human A 2/57 virus and between an avian (turkey/canada/63) and an equine (equi 2/miami/63) strain. The reactions were detected by strain-specific complement fixation tests and neuraminidase inhibition but not by haemagglutination-inhibition. Specific antiserum to the neuraminidase of an A 2/57 virus also reacted with the four avian viruses showing that it was the neuraminidase antigen on the avian and human A 2 virus that were antigenically closely related. The possibility that these viruses may have arisen by recombination between human and avian influenza viruses in nature is discussed.

This publication has 0 references indexed in Scilit: