Variation of food intake and body weight with estrous cycle, ovariectomy, and estradiol benzoate treatment in hamsters (Mesocricetus auratus).

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Abstract
Food intake and body wt of hamsters fluctuated systematically with the estrous cycle. Food intake and body wt were lowest when elevated endogenous estrogen levels were expected. Ovariectomized hamsters gained a significant amount of body wt compared with sham-operated animals. Replacement therapy with estradiol benzoate reduced the body wt and food intake of ovariectomized animals relative to oil-injected, ovariectomized control animals. The results were compared with similar data from rats. Estradiol operated to regulate food intake and body weight in both species.