Isolation and Characterization of an Endogenous Type C Virus of Rhesus Monkeys
- 25 May 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 204 (4395) , 841-842
- https://doi.org/10.1126/science.87013
Abstract
A type C retrovirus was isolated from a continuous cell line established from a spontaneous esophageal carcinoma of a rhesus monkey (Macaca mulata) by prolonged cocultivation with canine cells. A DNA transcript of the viral RNA hybridized to a high level and kinetic analysis indicated the presence of multiple copies of the viral genome in rhesus monkey DNA, showing that the virus is endogenous in this species. The rhesus monkey virus closely resembles, in several respects, an endogenous type C virus previously isolated from stumptailed macques (Macaca arctoides), aa species closely related to rhesus monkeys.This publication has 5 references indexed in Scilit:
- MAC-1, a new genetically transmitted type C virus of primates: “low frequency” activation from stumptail monkey cell culturesCell, 1978
- Baboons and their close relatives are unusual among primates in their ability to release nondefective endogenous type C virusesVirology, 1976
- [29] Analysis of repeating DNA sequences by reassociationPublished by Elsevier ,1974
- Quantitation of RNA Tumor Viruses and Viruslike Particles in Human Milk by Hybridization to Polyadenylic Acid SequencesScience, 1973