Autoimmune haemolytic anaemias. I. Serological studies with pure anti-immunoglobulin reagents.

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  • 1 September 1968
    • journal article
    • Vol. 3  (7) , 605-14
Abstract
In this paper the preparation and examination of pure antisera against immunoglobulins is described. The results of serological studies obtained with pure anti-IgG, anti-IgM and anti-IgA sera as well as an anti-complement serum and the blood of four patients with acquired haemolytic anaemia are discussed. The presence of incomplete warm autoantibodies belonging to the G, M and A classes of immunoglobulins was demonstrated. Further, evidence was obtained that warm haemolysins are a separate antibody category independent of the presence of incomplete warm autoantibodies.