Two HLA—D and DR Alleles are Associated with Coeliac Disease
- 1 October 1979
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 14 (4) , 309-316
- https://doi.org/10.1111/j.1399-0039.1979.tb00854.x
Abstract
A group of 45 children affected with Coeliac Disease (CD) was typed for HLA—A, B, C, D, and DR specificities. The most significant associations were found with two alleles of the D series, with both cellular and serological typing. It is suggested that the susceptibility to CD is determined by two different genes within the HLA region, the first in common with organ‐specific autoimmune diseases and associated with Dw3, the second possibly specific for CD and associated with Dw7.This publication has 16 references indexed in Scilit:
- Split of HLA-DRw2 into subtypic specificities closely correlated to two HLA-D productsImmunogenetics, 1978
- Proctosigmoiditis and coeliac disease.Archives of Disease in Childhood, 1978
- Heterogeneity in diabetes mellitus--update, 1978. Evidence for further genetic heterogeneity within juvenile-onset insulin-dependent diabetes mellitusDiabetes, 1978
- Genetics of Juvenile Diabetes MellitusNew England Journal of Medicine, 1977
- HLA-DW3 ASSOCIATED WITH CŒLIAC DISEASEThe Lancet, 1976
- SPECIFIC B-CELL ANTIGENS ASSOCIATED WITH GLUTEN-SENSITIVE ENTEROPATHY AND DERMATITIS HERPETIFORMISThe Lancet, 1976
- HLA Antigens in Dermatitis Herpetiformis and Coeliac DiseaseTissue Antigens, 1976
- HL-A8 AND HL-A12 IN CŒLIAC DISEASEThe Lancet, 1974
- EUROPEAN SOCIETY FOR PAEDIATRIC GASTROENTEROLOGYActa Paediatrica, 1970
- Inheritance of coeliac disease.Journal of Medical Genetics, 1969