Sensory Neuropeptides Contribute to Oedema Formation in Experimental Burns
- 1 January 1987
- journal article
- Published by Taylor & Francis in Scandinavian Journal of Plastic and Reconstructive Surgery
- Vol. 21 (3) , 291-292
- https://doi.org/10.3109/02844318709086463
Abstract
The role of primary sensory neuropeptides in experimental burns was investigated. It was shown that after scalding, substance P-like immunoreactivity is released into the lymphatic fluid of dogs. Substance P, injected intravenously, was shown to cause dose-dependent oedema formation in rat skin, as measured with the Evans blue-technique. Furthermore, capsaicin pretreatment, which depletes the neuropeptide content of primary sensory neurons, was shown to inhibit late oedema formation in rats.Keywords
This publication has 2 references indexed in Scilit:
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- Early and delayed œdema and increase in capillary permeability after burns of the skinThe Journal of Pathology and Bacteriology, 1958