Presence of Alpha-1-Antitrypsin on Mitogen-Stimulated Human Lymphocytes
Open Access
- 1 January 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 122 (1) , 24-26
- https://doi.org/10.4049/jimmunol.122.1.24
Abstract
Human lymphocytes that have undergone concanavalin A-induced blastogenetic transformation demonstrate surface alpha-1-antitrypsin by immunofluorescence when examined after 72 hr of culture, whereas unstimulated cells do not. These results may indicate a role for alpha-1-antitrypsin in lymphocyte blastogenesis.This publication has 5 references indexed in Scilit:
- A Cytotoxic Proteinase Isolated from Human LymphocytesThe Journal of Immunology, 1978
- The relationship between surface protease activity and the rate of cell proliferation in normal and transformed cellsBiochemical and Biophysical Research Communications, 1977
- In vitro stimulation of lymphocytes by neutral proteinases from human polymorphonuclear leukocyte granules.The Journal of Experimental Medicine, 1976
- Mitogenicity of thrombin and surface alterations on mouse splenocytesExperimental Cell Research, 1976
- α1-antitrypsin, an inhibitor for thrombin and plasminClinica Chimica Acta; International Journal of Clinical Chemistry, 1967