Synthesis of a peptidyl 2,2-difluoro-4-phenylbutyl ketone and its evaluation as an inhibitor of interleukin-1β converting enzyme.
- 31 December 1993
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 3 (12) , 2693-2698
- https://doi.org/10.1016/s0960-894x(01)80744-7
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Synthesis of a peptidyl difluoro ketone bearing the aspartic acid side chain: an inhibitor of interleukin-1.beta. converting enzymeThe Journal of Organic Chemistry, 1992
- A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytesNature, 1992
- Synthesis and N- and C-terminal extension of peptidyl α, α-difluoroalkyl ketonesTetrahedron Letters, 1992
- Interleukin-1 and interleukin-1 antagonismBlood, 1991
- Preparation of trifluoromethyl ketones and related fluorinated ketonesTetrahedron, 1991
- Fluorine-containing organozinc reagents. V.Tetrahedron Letters, 1988
- Readily accessible 12-I-5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketonesThe Journal of Organic Chemistry, 1983
- New acyl anion equivalent. A short route to the enol lactam intermediate in cytochalasin synthesisTetrahedron Letters, 1981
- Application of Dialkylaminosulfur Trifluorides in the Synthesis of Fluoroorganic CompoundsSynthesis, 1973
- A GENERAL REACTION OF AMINO ACIDSPublished by Elsevier ,1928