Answers to the Antiphospholipid-Antibody Syndrome?
- 13 April 1995
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 332 (15) , 1025-1027
- https://doi.org/10.1056/nejm199504133321510
Abstract
Truly elegant clinical science defines syndromes with precision, delineates pathogenic mechanisms, and compares treatments in prospective randomized trials. Conventional clinical science lacks precision and applies empirical remedies. According to these definitions, the clinical science focused on the antiphospholipid-antibody syndrome is conventional now, but on the verge of becoming elegant.The diagnosis of the antiphospholipid-antibody syndrome1 requires that a patient have recurrent clinical events (such as thromboses or fetal loss) and an antiphospholipid antibody (such as anticardiolipin antibody or lupus anticoagulant). The syndrome is “primary” if there is no accompanying autoimmune disease and “secondary” if the patient also has systemic lupus . . .Keywords
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