Tissue Nucleotides in Experimental Hydrocortisone Diabetes in Guinea Pigs

Publisher Website
Google Scholar
Abstract
Guinea pigs have been made diabetic by subcutaneous administration of hydrocortisone. Nucleotides and related compounds have been determined in liver, erythrocytes and pancreas of diabetic and normal animals by utilization of anion exchange chromatography and specific enzymatic assays. Changes in components of pancreas and erythrocytes were minor and of questionable significance. The decrease in uridine diphosphate glucose and uridine diphosphate N-acetylglucosamine in liver of diabetic animals was highly significant. The diabetic animals also showed an increased level of adenosine triphosphate in liver.

This publication has 0 references indexed in Scilit: