HEART DISEASE OF UNKNOWN CAUSE IN SIBLINGS
- 1 July 1957
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 47 (1) , 49-58
- https://doi.org/10.7326/0003-4819-47-1-49
Abstract
The occurrence of heart disease of unknown etiology in 10 pairs of siblings is reported. Post mortem examination was performed in 7 cases. The pathological findings varied, showing endocardial fibroelastosis, myocardial hypertrophy and myocardial fibrosis. Progressive congestive heart failure, often right-sided and mimicking constrictive pericarditis, peripheral emboli and a large heart often without significant murmurs were found clinically. The presence of heart disease of this type in siblings suggests that the primary defect may be congenital.Keywords
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