Xylazine hydrochloride‐induced hyperglycemia and hypoinsulinemia in thoroughbred horses
- 1 December 1982
- journal article
- Published by Wiley in Journal of Veterinary Pharmacology and Therapeutics
- Vol. 5 (4) , 241-245
- https://doi.org/10.1111/j.1365-2885.1982.tb00439.x
Abstract
The effects of intravenous xylazine (1.1 mg/kg) were studied in six thoroughbred horses (five mares and a stallion). Plasma glucose concentration increased to 168% of control at 45 min and decreased to 112% of control at 180 min. Insulin had decreased to 31% of control at 15 min. Thereafter, insulin concentration increased, reaching its highest concentration at 150 min. The mechanism for these changes is not fully understood and further investigation is indicated.Keywords
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