CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. III. AMINO ACID COMPOSITION OF PLASMA PROTEINS 1

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Abstract
:[long dash]As a preliminary contribution to the understanding of the composition of the human plasma proteins, amino acid analyses have been carried out on normal human serum albumin, the human [gamma]-globulins of importance in immunity, a fraction rich in [beta]-globulin, and human fibrinogen and fibrin. Comparable analytical studies on the serum albumin of cattle and the horse are included for comparison. Highly significant differences in the amino acid distribution have been noted, among them being the high % of hydroxy amino acids in the [gamma]-globulins, the very low content of tryptophane in the albumins and the absence of methionine in horse serum albumin.