STUDY, BY MEANS OF CORRESPONDENCE-ANALYSIS, OF STRUCTURE ACTIVITY RELATIONSHIP OF DIPHENYLETHYLENES AND TRIPHENYLETHYLENE IN 2 BIOCHEMICAL TESTS

  • 1 January 1982
    • journal article
    • research article
    • Vol. 294  (15) , 731-734
Abstract
The biochemical activity of .apprx. 50 original molecules of di- and triphenylethylene structures was studied by correspondence analysis. Pharmacological experiments were made on glutamate dehydrogenase and prostaglandin synthetase. A typology of several molecular groups is established and the effects of various substituents are specified.

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