Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex.
Open Access
- 1 November 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (11) , 5131-5134
- https://doi.org/10.1073/pnas.74.11.5131
Abstract
Alloantisera directed against the alloantigens determined by the I-E and I-C subregions of the murine major histocompatibility complex precipitate 2 components that have MW of 35,000 and 29,000. These components, when analyzed by partial NH2-terminal sequencing, show no homology to 2 components of similar size determined by the I-A subregion. The large chain determined by the murine I-E and/or I-C subregion is homologous to the large chain of the human HLA-D region alloantigen, although the small chains isolated from these 2 species do not display any such homology.Keywords
This publication has 34 references indexed in Scilit:
- Cell-free synthesis of the fourth component of guinea pig complement (C4): identification of a precursor of serum C4 (pro-C4).Proceedings of the National Academy of Sciences, 1977
- MLC-activating HLA-D determinants: identification, tissue distribution, and significance.1977
- Partial amino acid sequences of Ia alloantigens.1977
- [27] Microsequence analysis in automated spinning-cup sequenatorsPublished by Elsevier ,1977
- Serological and Functional Evidence for Further Subdivision of the I Regions of the H-2 Gene ComplexCold Spring Harbor Symposia on Quantitative Biology, 1977
- Genetics and Serology of HL-A-linked Human Ia AntigensCold Spring Harbor Symposia on Quantitative Biology, 1977
- Chemical and Immunological Characterization of HL-A-linked B-lymphocyte AlloantigensPublished by Cold Spring Harbor Laboratory ,1977
- Human Ia Antigens -- Purification and Molecular StructurePublished by Cold Spring Harbor Laboratory ,1977
- Chemical Characterization of Products of the H-2 ComplexCold Spring Harbor Symposia on Quantitative Biology, 1977
- Suppressive and Enhancing T-cell Factors as I-region Gene Products: Properties and the Subregion AssignmentPublished by Cold Spring Harbor Laboratory ,1977