Genetic Analysis of the Serum Level of IgG2 and Total Protein in Red Danish Cattle

Abstract
Concentrations of the total protein and the immunoglobulinsubclass IgG2 in serum were determined from unselected half-sib groups of registered herds of Red Danish Cattle. The sampling was made in April 1972, comprising individuals from 4 to 38 months of age. Correction for age reduced the variance for total protein and IgG2 by 11 and 12%, respectively. Higher ages, in both cases, corresponded with higher values. The serum-IgG2 concentration corrected for total protein and age showed an almost normal distribution ranging from about 0 mg/100 ml to more than 700 mg/100 ml. The simple correlation between total protein and IgG2 in serum was .49. However, this includes some autocorrelation. Heritability estimates of the two traits suggested a slight genetic influence on total protein (h2 = .09 ± .07) and IgG2 (h2 = .12 ± .08).

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