Comparativein-vitro activity of ciprofloxacin against non-fermenters
- 1 April 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 15 (4) , 457-462
- https://doi.org/10.1093/jac/15.4.457
Abstract
Theut-vitro activity of ciprofloxacin, a quinolone-carboxylic acid derivative, was compared with those of carbenicillin, azlocilhn, cefsulodin, ccftazidime, tobramycin and amikacin against 187 non-fermenters. Only one of the 131 strains of Pseudomonas spp was not inhibited by 1 mg/1 of ciprofloxacin, while these isolates appeared highly resistant to carbenicillin, azlocilhn and cefsulodin. Ciprofloxacin was also the best agent againstFlavobacterium, AlcaJtgenes faecaJis andAcinetobacter calcoaceticus with MIC90's respectively of 0–5, 4 and 8 mg/1. This new compound appeared bactericidal, and we found a small or no inoculum effect with ciprofloxacin.Keywords
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