The Conductance of Conjugated and Unconjugated Bile Acid Salts in Aqueous Solutions. Bile Acids and Steroids. 80.

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Abstract
The equivalent conductances of aqueous solutions of the sodium salts of cholic, taurocholic, glycocholic, deoxycholic, taurodeoxycholic, glycodeoxycholic and dehydrocholic acids in the concentration range from 0.002 to 0.5M were measured at 40[degree]C. All these bile salts were found to differ from a normal uni-univalent elec-trolyte in their conductance behavior. The beginning association leads to a greater than normal increase in the conductance in cholate and deoxycholate solutions. The advancement of the association in more concentrated solutions causes the slope of the curve plotting equivalent conductance against root concentration to decrease. With deoxycholate this results in a maximum which is followed by a minimum, while with cholate only a change in the slope of the curve occurs. The variations in the courses of the conductance curves are less pronounced for bile salts than for paraffin chain salts and therefore an evaluation of the critical concentration from the conductance data is not possible for bile acid salts. The conductance curves for the conjugated bile acid salts do not differ essentially from those for the unconjugated bile acid salts, which may be taken to indicate that the progress of association is similar.