Water distribution in creams prepared using cetostearyl alcohol and cetrimide
- 1 August 1987
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 39 (8) , 642-643
- https://doi.org/10.1111/j.2042-7158.1987.tb03443.x
Abstract
The water distribution in an antiseptic cream formulation prepared using cetostearyl alcohol and cetrimide has been studied using thermogravimetric analysis, differential scanning calorimetry, ultracentrifugation and scanning electron microscopy. In addition to a free water phase two types of interlamellarly fixed water were found, one associated with the liquid crystalline network around the oil droplets and one associated with the liquid crystalline network of the bulk. The latter was in equilibrium with the free water and can be classed as freely drainable.Keywords
This publication has 1 reference indexed in Scilit:
- A systematic microscopical examination of gels and emulsions containing cetrimide and cetostearyl alcoholInternational Journal of Pharmaceutics, 1985