Abstract
The age-adjusted rate of death from breast cancer in the United States was 24% lower in 2003 than it was in 1989,1 a decline that has been attributed principally to both the role of mammography in detecting early-stage tumors and improvements in therapy. Indeed, early diagnosis and therapy have been the cornerstone of efforts to control breast cancer, since a readily accessible preventive strategy for women with an average risk has been elusive. Prevention is clearly the preferable strategy for controlling cancer, but for the foreseeable future, the control of breast cancer will depend mostly on early detection, careful diagnostic . . .