CAUSTIC EFFECT OF SODIUM SULFATHIAZOLE SOLUTION ON NASAL MUCOUS MEMBRANES
- 2 May 1942
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 119 (1) , 7-8
- https://doi.org/10.1001/jama.1942.02830180009004
Abstract
It has long been the hope of rhinologists to find a medicament which, when applied in the nose and sinuses, would be bactericidal or at least bacteriostatic to pathogenic organisms yet spare the delicate ciliated membranes. Turnbull's1 favorable recommendation of a nasal spray of 5 per cent sodium sulfathiazole no doubt raised such hopes. It has been difficult at large for specialists in otolaryngology to accept this recommendation. The complexity of chronic sinusitis is known too well to expect an eradication of infection. degenerative pathologic changes and the constitutional factors involved by the use of one medicament. Chronic sinusitis is not a specific disease, and success cannot be expected when it is so treated. Fletcher2 has reported on the caustic action of sodium sulfathiazole in the maxillary sinus in 1 case. The present report describes the effect of solutions of sodium sulfathiazole in 5 and 30 per centThis publication has 0 references indexed in Scilit: