Intrauterine Transfusion for Haemolytic Disease of the Newborn

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Abstract
Amniocente sis and spectrophotometric examination of the liquor amnli have been performed on antenatal patients with high titer Rh antibodies. If the optical density peak at 450 m[mu] has indicated very severe hemolytic disease in the fetus then intraperitoneal transfusion has been given. Liley''s technique for this has been modified by omitting the injection of Urografin and antibiotics into the amniotic cavity. Four infants had one transfusion and 1 infant had 2 transfusions prior to delivery. One infant with hydrops fetalis was born too soon and could not be saved. Another infant had his hemolytic disease controlled but died after cardiac arrest during exchange transfusion. The other 3 have survived following exchange transfusion.

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