Neurosyphilis after treatment of latent syphilis with benzathine penicillin.
- 1 April 1986
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 62 (2) , 129-131
- https://doi.org/10.1136/sti.62.2.129
Abstract
Two patients developed neurosyphilis after treatment of latent syphilis with intramuscular benzathine penicillin. The cases confirm recent investigations that show that neither benzathine penicillin nor procaine penicillin in the standard doses results in treponemicidal concentrations of penicillin in cerebrospinal fluid. Neurosyphilis can be treated effectively by intravenous benzylpenicillin infusions of 18 to 21.6 g daily for 15 days.This publication has 17 references indexed in Scilit:
- Penicillin concentrations in serum and cerebrospinal fluid after intramuscular injection of aqueous procaine penicillin 0.6 MU with and without probenecid.Sexually Transmitted Infections, 1984
- Penicillin concentrations in blood and spinal fluid after a single intramuscular injection of penicillin G benzathineEuropean Journal of Clinical Microbiology & Infectious Diseases, 1984
- [Neurosyphilis today].1982
- Neurosyphilis heuteDermatology, 1982
- Persistence of Treponema pallidum following penicillin G therapy. Report of two casesJAMA, 1976
- Penicillin treatment of neurosyphilis. Are recommended dosages sufficient?JAMA, 1975
- Penicillin Treatment of NeurosyphilisPublished by American Medical Association (AMA) ,1975
- Neurosyphilis. A study of 241 patientsPublished by American Medical Association (AMA) ,1972