Development and Secretion of the Blood Group Factor O in the Newborn

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Abstract
The development of the property O in the newborn and in young children, investigated from the point of view of the agglutinability and group-specific absorbing power with an immune anti-Shigella dysenteriae goat serum, is comparable to that of the agglutinogens A and B. The agglutinability and absorbing power are both extremely poor at birth, but increase, until after 3-5 yrs. their values equal those of the adult. Saliva from newborn and children of group O of the "secretor" type, neutralizes anti-O serum approx. to the same degree as saliva of adults of group O. The results obtained seem to contradict recent investigations which consider the so-called anti-O sera to have only an anti-H specificity. Probably, anti-O sera contain a mixture of serologically related antibodies to some of which, however, cannot be denied an anti-O specificity in the strict sense.

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