Ionizing Radiation Decreases Veratridine-Stimulated Uptake of Sodium in Rat Brain Synaptosomes
- 3 June 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 220 (4601) , 1073-1074
- https://doi.org/10.1126/science.6302846
Abstract
Veratridine-stimulated uptake of sodium-22 in brain synaptosomes was significantly reduced by ionizing radiation over a dose range of 10 to 1000 rads. The response was dose-dependent and involved a decrease in the maximum effect of veratridine on uptake. The central nervous system may be more sensitive to ionizing radiation than generally thought, perhaps through a loss of the ability of the sodium channel to respond properly to stimulation.This publication has 11 references indexed in Scilit:
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