Evidence of major role of the intestine in cholesterol synthesis in the adult male rat

1 June 1975

journal article
Published by Springer Nature in Cellular and Molecular Life Sciences

Vol. 31 (6) , 627-629
https://doi.org/10.1007/bf01944594

Abstract

By a new in vivo method using 1-¹⁴C-acetate, it becomes apparent that the intestine is the main organ concerned in cholesterol synthesis. The liver contributes a mere 13.5% to the total. These results challenge the traditional theory which considers the liver as responsible for producing most of cholesterol synthesized by the rat.

Keywords

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