Studies on uracil derivatives and analogues. Part 8. A non-catalytic method for the conversion of uracil derivatives into dihydrouracil derivatives

Abstract
A mild and highly efficient method for the reduction of the 5,6-double bond of N-alkylated uracils with lithium tri-s-butylborohydride gives the corresponding 5,6-dihydro derivatives. The method can also be used for alkylation of the 5-position of N-alkyluracils to give 5-alkyl-5,6-dihydrouracil derivatives.

This publication has 0 references indexed in Scilit: