A two-state homology model of the hERG K+ channel: application to ligand binding
- 3 February 2005
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (6) , 1737-1741
- https://doi.org/10.1016/j.bmcl.2005.01.008
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Physicochemical Features of the hERG Channel Drug Binding SiteJournal of Biological Chemistry, 2004
- Glide: A New Approach for Rapid, Accurate Docking and Scoring. 2. Enrichment Factors in Database ScreeningJournal of Medicinal Chemistry, 2004
- X-ray structure of a voltage-dependent K+ channelNature, 2003
- Understanding the Structure−Activity Relationship of the Human Ether-a-go-go-Related Gene Cardiac K+ Channel. A Model for Bad BehaviorJournal of Medicinal Chemistry, 2003
- Molecular Determinants of Voltage-dependent Human Ether-a-Go-Go Related Gene (HERG) K+ Channel BlockJournal of Biological Chemistry, 2002
- The open pore conformation of potassium channelsNature, 2002
- A structural basis for drug-induced long QT syndromeProceedings of the National Academy of Sciences, 2000
- All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of ProteinsThe Journal of Physical Chemistry B, 1998
- The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambinJournal of the American Chemical Society, 1988
- CHARMM: A program for macromolecular energy, minimization, and dynamics calculationsJournal of Computational Chemistry, 1983