STUDIES OF THE EFFECT OF PARA-AMINOBENZOIC ACID, FOLIC ACID, AND SULFANILAMIDE ON DEXTRAN SYNTHESIS BY LEUCONOSTOC
- 1 August 1949
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 58 (2) , 143-149
- https://doi.org/10.1128/jb.58.2.143-149.1949
Abstract
Two folic acid-dependent strains, L. mesenteroides 683 and L. dextranicum 8086, and 2 folic acid-independent strains, L. mesenteroides 535 and L. dextranicum elai, were employed. Low levels of p-aminobenzoic acid failed to stimulate dextran synthesis, while higher concns. retarded growth and polysaccharide formation. With folic acid-independent strains, sulfanilamide produced a greater inhibition of acid production than of dextran synthesis. With added folic acid, sulfanilamide in high concn. did not retard dextran formation by strains dependent on this vitamin. Thus p-aminobenzoic acid is not involved in dextran synthesis by these strains of Leuconostoc.This publication has 7 references indexed in Scilit:
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