Abstract
A girl of 41/2 years presented with enlargement of the cervical lymph nodes and spleen, followed by anemia, leucopenia, fever and enlargement of the liver. Jaundice, thrombocytopenia and a bleeding tendency appeared terminally. A lymph node removed during life showed appearances typical of Hodgkin''s disease but at death the reticulo-endothelial system was replaced by a proliferation of phagocytic histiocytes and giant cells.

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